Anatomy & Physiology · Body Systems, Homeostasis & Health

Your body is a system, and Detroit tests it every day.

From runners on the Detroit Free Press Marathon course to children living near highways with asthma, human biology shows up in every Detroit neighborhood. This unit covers body systems, feedback loops that keep the body stable, and how the environment shapes health.

NGSS Standards Addressed High School

  • HS-LS1-2 Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
  • HS-LS1-3 Plan and conduct an investigation to provide evidence that feedback mechanisms maintain homeostasis.
  • HS-LS1-7 Use a model to illustrate that cellular respiration is a chemical process in which bonds of food and oxygen molecules are broken and new bonds form, with a net transfer of energy.

NGSS Standards Addressed Middle School

  • MS-LS1-3 Use argument supported by evidence for how the body is a system of interacting subsystems composed of groups of cells.
  • MS-LS1-7 Develop a model to describe how food is rearranged through chemical reactions forming new molecules that support growth and release energy.
  • MS-LS1-8 Gather and synthesize information that sensory receptors respond to stimuli by sending messages to the brain.
Warm-Up

Bell-Ringers

Project one at the start of class. Each has a click-to-reveal discussion note. Try Project Mode for full-screen slides. More formats (Notice and Wonder, CER, Fact or Fiction, and more) are in the Bell-Ringer Bank.

Sports

During the Detroit Free Press Marathon, runners' heart rates rise and they sweat heavily. Describe the feedback loop that keeps body temperature near 37°C, naming the stimulus, receptor, control center, and effectors.

Discussion notes
Stimulus: rising body temperature. Receptors: temperature sensors in skin and brain. Control center: the hypothalamus. Effectors: sweat glands and skin blood vessels. Response: sweating and wider skin blood vessels release heat, temperature falls, and the response shuts off. This is negative feedback.
Health

Detroit has among the highest childhood asthma rates in Michigan. In an idealized model, airflow resistance scales as 1 / r⁴. If inflammation halves an airway's radius, by what factor does resistance rise, and why does that matter?

Discussion notes
Halving the radius multiplies resistance by 2⁴ = 16. A small narrowing of the airway causes a very large drop in airflow, which is why swelling and mucus make breathing so difficult during an asthma attack.
Housing

Dust from old lead paint can enter a child's body and affect the developing nervous system. Which body systems are involved in the path from dust on a windowsill to the brain?

Discussion notes
Hand-to-mouth contact brings dust into the digestive system, where lead is absorbed. The circulatory system carries it through the body, and lead can then affect the nervous system, especially in children whose brains are still developing.
Sports

When you run, your breathing and heart rate speed up. What do your muscle cells need more of, and how do the respiratory and circulatory systems deliver it?

Discussion notes
Muscle cells need more oxygen to release energy from food. The respiratory system brings oxygen into the lungs, and the circulatory system (heart and blood) carries it to the muscles. Faster breathing and heartbeat increase that delivery.
Music

A loud concert at a Detroit venue can leave your ears ringing. Name the sense organ and the path sound takes to become a signal in the brain.

Discussion notes
The ear. Sound waves vibrate the eardrum and tiny bones, which move fluid in the cochlea. Hair cells convert the vibrations to nerve signals that the auditory nerve sends to the brain. Very loud sound can permanently damage the hair cells.
Health

After a meal from Eastern Market, how do your digestive and circulatory systems work together?

Discussion notes
Digestion breaks food into small nutrients that pass into the blood. The circulatory system then carries those nutrients to every cell, where they are used for energy and growth.
Hands-On

Labs

Heart Rate & Recovery: Training for the Detroit Marathon

45 minPairsHomeostasis and feedback

Students measure resting, exercise, and recovery heart and breathing rates (voluntary participation) and explain the results with feedback loops and cellular respiration.

Airway Model: Why a Little Narrowing Matters

40 minSmall groupsRespiratory system model

Students time water draining through tubes of different widths to see how small changes in width cause large changes in flow, then connect the model to asthma.

Explore

Simulations

Original on The Lab

Airway Flow Explorer

Narrow a model airway and watch flow resistance, airflow, and the effect of an asthma trigger change with radius.

Launch Simulation →

Fluid Pressure and Flow

PhET Interactive Simulations — explore how pipe width and pressure change flow, a model for blood vessels and airways.

Open Simulation →

Neuron

PhET Interactive Simulations — see how a nerve cell sends an electrical signal, connecting to sensory receptors and the nervous system.

Open Simulation →

MiEJScreen (Michigan EGLE)

Michigan's public environmental justice mapping tool — explore air-related and community indicators around Detroit neighborhoods.

Open Tool →
Go Further

Project Ideas

Model

Homeostasis Feedback-Loop Poster

Build a labeled model of one feedback loop (body temperature, blood glucose, or hydration) with a stimulus, receptor, control center, effector, and response.

Action plan

Asthma Trigger Reduction Plan

Using reliable public-health sources, design a plan to reduce asthma triggers at home or school and explain the biology behind each action.

Campaign

Decibels and Hearing Safety Campaign

Measure sound levels at school events with a phone app (noting its limits), compare them with published exposure guidance, and design a hearing-protection campaign.

Role play

Body Systems Relay Model

Act out or illustrate how the digestive, circulatory, respiratory, and nervous systems pass materials and signals during a run.

Build challenge

Working Lung Model

Build a model lung from a bottle, balloons, and a straw, and explain what each part represents and how breathing works.

Experiment

Reaction Time Experiment

Use a ruler-drop test to measure reaction time, graph class results, and trace the path of the signal through the nervous system.

Assess

Show What You Know: Exit Ticket

Three quick questions to close the lesson. Answers are hidden until you click. Use Project Mode to display them full-screen.

Question 1

Describe the negative feedback loop that keeps a runner's body temperature near normal during a marathon.

Answer
Temperature receptors detect warming and signal the hypothalamus. Effectors respond: skin blood vessels widen and sweat glands release sweat. Heat is lost, temperature falls, and the response shuts off.
Question 2

If an airway's radius is cut in half, about how much does flow resistance increase in an idealized model, and why does that matter for asthma?

Answer
Resistance scales roughly with 1 / r&sup4;, so half the radius gives about 16 times the resistance. Small amounts of airway narrowing therefore cause large drops in airflow.
Question 3

Trace how lead dust from old paint could move from a windowsill to a child's developing brain, naming the body systems involved.

Answer
Hand-to-mouth contact brings dust into the digestive system, where lead is absorbed. The circulatory system carries it throughout the body, and it can affect the nervous system, especially in children.
Question 1

Why do your breathing and heart rate increase when you run?

Answer
Active muscle cells need more oxygen to release energy from food. Faster breathing brings in more oxygen and a faster heart rate delivers it to the muscles.
Question 2

Name the sense organ and two parts involved when you hear music.

Answer
The ear. Sound waves vibrate the eardrum and small bones, and the cochlea's hair cells convert the vibrations into signals sent to the brain by the auditory nerve.
Question 3

How do the digestive and circulatory systems work together after you eat?

Answer
Digestion breaks food into small nutrients that are absorbed into the blood. The circulatory system carries those nutrients to every cell.

View project rubrics →

Why Does This Matter?

Anatomy & Physiology, built on Detroit

Sports

The Detroit Free Press Marathon, which crosses the U.S.–Canada border, and the city's pro and school teams turn heart, lung, and muscle physiology into something students can see and feel.

Housing

Home conditions such as mold, pests, and lead paint dust affect asthma and development, linking body systems directly to Detroit's housing stock.

Music

Detroit's music scene is a hearing-health lesson: understanding how the ear works shows why concert volume and listening habits matter.

Technology

Detroit's hospitals and Wayne State University research labs apply imaging, monitoring, and wearable technology to understand how body systems work and fail.

Careers

Who works on this in Detroit?

Real roles and organizations in and around the city where this science is part of the job.

Respiratory therapist

Henry Ford Health, Detroit Medical Center

Treats patients with asthma, COPD, and other breathing problems using airway and ventilation therapies.

Public health nurse / community health worker

Detroit Health Department and neighborhood clinics

Helps families manage asthma triggers, lead exposure, nutrition, and preventive care.

Athletic trainer / sports physiologist

Professional teams and school athletic programs

Monitors heart rate, hydration, and recovery to keep athletes performing safely.

Audiologist

Hospital and university hearing clinics

Tests hearing, treats hearing loss, and teaches hearing protection to musicians and fans.

Biomedical researcher

Wayne State University School of Medicine, Karmanos Cancer Institute

Studies how body systems work and fail, and develops new treatments.